Week 6: Drugs for Diabetes

Be able to:

• describe the physiological role of insulin and the basic pathophysiology of type 1 and 2 diabetes mellitus (REVIEW)
• describe the uses of insulin therapy in type 1 and 2 diabetic patients
• compare the different formulations of insulin and outline how they are used in daily regimens
• describe the mechanisms of action, major adverse effects, and precautions associated with metformin, sulfonylureas, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 analogues, and sodium-glucose co-transporter 2 inhibitors
• outline the general approach to drug therapy in patients with type 2 diabetes.